Enzyme activities are currently determined by spectrophotometry on muscle biopsy samples. The tests reveal if the patient presents any deficiency in one of the particular enzymes analyzed (no or very low activity).

Now available

Glycolytic Enzyme Panel (GEP) includes: Total phosphorylase, Phosphofructokinase (PFK), Phosphoglycerate kinase (PGK), Lactate Dehydrogenase (LDH), Aldolase (ALD), Phosphoglycerate mutase (PGM). All these enzymes are involved in the metabolic pathway using glycogen or glucose and glycogen energy for skeletal muscle contraction (glycolysis). Glycolytic Enzyme Panel Information Sheet Glycolytic Enzyme Panel Form

Electron Transport Chain Panel (ETCP) includes: Succinate Dehydrogenase (SDH), Succinate/Cytochrome C Reductase (SCCR), NADH/Cytochrome C Reductase (NCCR), Cytochrome C Oxidase (COX) These enzymes regulate key steps in the electron transport across the mitochondrial membranes which is the third part of the metabolic pathway involved in skeletal muscle contraction. Citrate Synthase (CS) is a TCA cycle enzyme used as a marker for mitochondrial prediction.