This study is being done to understand the consequences of burn injuries on temperature control.
•18-55 year old men or women
•Healthy, although subjects with controlled hypertension or hypercholesterolemia will be permitted to participate
•Experienced a burn injury covering at least 20% of your body
•Well-healed burn injuries
•Able to speak and read English
• Individuals who have been diagnosed as having or have been prescribed and/or are taking medications for : AIDS, AIDS Related Complex, HIV, Tuberculosis, Cirrhosis, Renal insufficiency (defined by creatinine >3.0 mg/dl), Hepatic disease (defined by elevated liver enzymes or bilirubin >3.0 mg/dl), Coronary artery disease, Congestive heart failure, Uncontrolled asthma or pulmonary disease (e.g. emphysema, COPD), Associated head injuries requiring specific treatment, and/or Mental retardation or autism or any other mental disorder, which makes it impossible to participate in an exercise program.
•Subjects who have a pathological ECG or uncontrolled resting blood pressure greater than 150/90 mmHG
•Unable to exercise due to physical impediments
•Pregnant or breast feeding
•Positive urine drug screen
Participation in this study will require four (4) visits to the laboratory, with a total time commitment of approximately fifteen (15) hours. Study procedures include exercising and monitoring heart rate and rhythm, blood pressure, body temperature and skin temperature. Qualified individuals will be compensated.
The Thermal and Vascular Physiology Laboratory at 214.345.4737IEEMThermoregulation@TexasHealth.orgor